Endocrine Abstracts

Objective: To establish possible associations of the polymorphism of the insulin receptor substrate−1 (IRS-1) gene with the severity of various components of metabolic syndrome in patients with arterial hypertension (AH). We examined 187 patients with AH aged 45–55 years (with history of hypertension less than 5 years, unsystematic administration of antihypertensive drugs and/or failure to achieve target blood pressure (BP) levels when prescribing drug therapy). The...